Mitochondrial Impairment in Sarcopenia
Sarcopenia is defined by the age-related loss of skeletal muscle quality, which relies on mitochondrial homeostasis.During aging, several mitochondrial features such as bioenergetics, dynamics, biogenesis, and selective autophagy (mitophagy) are altered and impinge on protein homeostasis, resulting in loss of muscle mass and function.Thus, mitochon